Combinations ; - see below
| Brand Name | Manufacturer Name | Distributor | Drug Strength | Packaging | Formulation | Formulation Strength | Price |
|---|---|---|---|---|---|---|---|
| trial3 | Abic | ACE Pharmaceuticals Ltd | 10 | 100 | Tablet | per tablet | KES 20000 |
| Ziagen | GlaxoSmithkline | Surgipharm Ltd | 300mg | 60 | Tablet | per tablet | KES 2,934.75 |
| Ziagen | GlaxoSmithkline | Surgipharm Ltd | 20mg | 240ml | Syrup | per 5ML | KES 4,113.20 |
| Abacavir More info | |
|---|---|
| Mode Of Action | Nucleoside reverse transcriptase inhibitors (NRTIs) that are converted by cellular cells? enzymes to active phosporylated metabolites that inhibit viral reverse transcriptase and viral DNA synthesis. |
| Drug Indication | HIV infection in combination with other ARVs. |
| Precautions | Hepatic impairment; patients weighing less than 40kg should not be given ABC in fixed combination with AZT and 3TC; reduce dose in cases or renal impairment. |
| Contra-Indications | Pregnancy and breastfeeding. |
| Side Effects | Serious allergic reactions (stop treatment and do not rechallenge), GI disturbances, fever, headache, fatigue, lactic acidosis. |
| Dosage | HIV infection in combination with other antiretroviral drugs: 600mg daily in 1-2 divided doses; Child 3months-12 years, 8mg/kg (max. 300mg) twice daily or 16mg/kg (max. 600mg) once daily or Body-weight 14-21kg, 150mg twice daily or 300mg once daily; Body-weight 21-30kg, 150mg in the morning and 300mg in the evening or 450mg once daily; Body-weight over 30kg, 300mg twice daily or 600mg once daily, Child 12-18 years, 300mg twice daily or 600mg once daily. |
| Pregnancy Category | Category C |
| Pregnancy Category Description | Drugs which, owing to their pharmacological effects, or may be suspected of causing detrimental effects on human foetus or neonates without causing malfunctions. These effects may be reversible |
| Drug Category | DRUGS ACTING ON INFECTIONS |
| Drug Sub-Category | Hiv Chemotherapy |